We all know stress is dangerous to health. Cells have different ways to cope with strains from our environment, whether a deadline, viruses, UV rays or toxic food. But sometimes, stress is good! One stress response is senescence, and this could help find new treatments for chronic inflammation.
One of the ways human cells protect themselves from becoming cancerous is to force a kind of premature aging known as senescence, which stops the cells from growing and dividing. But while this suppresses cancer, it has a dark side. Senescence is associated with normal aging—these cells build up in tissue, eventually causing hyper-inflammation and age-related diseases.
Chronic Inflammation according to science:
“While short-term inflammation can help stop cancer from starting, the problem is that long-term, chronic inflammation can lead to tissue destruction, aging, and even, paradoxically, can help cancer to grow and spread,” said study author Zhixun Dou, PhD.
Future therapy centers around designing a small molecule that could halt the dark side of senescence in order to treat age-related diseases, especially those related to chronic inflammation such as arthritis and neurodegeneration. The research might also find ways of treating graying hair and hair loss!Reference